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4-Fluorococaine inhibits a reuptake of dopamine, but is a much stronger serotonin reuptake inhibitor. This has lead to various results in animal studies. 4Fluorococaine has the same potential as cocaine, but may be much more powerful as a result of the stronger reuptake of serotonin. 4Fluorococaine can therefor not be compared to CFT or 2′-hydroxy analogue salicylmethylecgonine.

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